CD66b (CEACAM8) monoclonal antibody (PE) (AGIM0192)
- SKU:
- AGIM0192
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG1 kappa.
- Clone:
- 6/40c
- Conjugation:
- PE
- Applications:
- FC
Description
system_update_altDatasheet
| Product Name: | CD66b (CEACAM8) monoclonal antibody (PE) |
| Product Code: | AGIM0192 |
| Size: | 500 µL |
| Reactivity: | Human |
| Clone: | 6/40c |
| Applications: | Flow Cytometry |
| Conjugate: | PE |
| Isotype: | IgG1 kappa. |
| Host Species: | Mouse |
| Storage: | Store at 4°C. Avoid prolonged exposure to light. |
| Uniprot: | P31997 |
| Background: | CD66b, also known as CEACAM8 (Carcinoembryonic antigen-related (CEA) cell adhesion molecule 8, is a glycosyl phosphatidyl inositol- (GPI-) anchored glycoprotein. CD66b and related genes make up the CEA family belonging to the immunoglobulin superfamily. It is involved in cell cell communication*. In contrast to other members of the CEACAM gene family it does NOT serve as pathogen receptor (e.g. for Helicobacter pylori, Neisseria, Moraxella, Candida albicans). Immunologically CEACAMs are characterized as members of the CD66 cluster of differentiation. Antibodies to CD66b are commonly used in flow cytometry to distinguish granulocytes from other subtypes of leukocytes (B- and T-cells, NK-cells, Monocytes, DCs) In adults CEACAM8 is expressed in granulocytes together with CEACAM1, CEACAM3 and CEACAM6. |
| UniProt Protein Function: | CEACAM8: Belongs to the immunoglobulin superfamily. CEA family. |
| UniProt Protein Details: | Protein type:Immunoglobulin superfamily; Membrane protein, integral; Membrane protein, GPI anchor Chromosomal Location of Human Ortholog: 19q13.2 Cellular Component: extracellular space; integral to plasma membrane; plasma membrane Biological Process: immune response; blood coagulation; leukocyte migration |
| UniProt Code: | P31997 |
| NCBI GenInfo Identifier: | 21314600 |
| NCBI Gene ID: | 1088 |
| NCBI Accession: | NP_001807.2 |
| UniProt Secondary Accession: | P31997,O60399, Q16574, |
| Molecular Weight: | 38,154 Da |
| NCBI Full Name: | carcinoembryonic antigen-related cell adhesion molecule 8 |
| UniProt Protein Name: | Carcinoembryonic antigen-related cell adhesion molecule 8 |
| UniProt Synonym Protein Names: | CD67 antigen; Carcinoembryonic antigen CGM6; Non-specific cross-reacting antigen NCA-95 |
| UniProt Gene Name: | CEACAM8 |
| UniProt Entry Name: | CEAM8_HUMAN |
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