CD63 Monoclonal Antibody (CAB22343)
- SKU:
- CAB22343
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | CD63 Monoclonal Antibody |
| Product Code: | CAB22343 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC51690 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | A375, RAW264.7, Rat kidney |
| Cellular Location: | Cell membrane, Endosome, Late endosome membrane, Lysosome membrane, Melanosome, Multi-pass membrane protein, multivesicular body |
| Customer Validation: | WB(Mus musculus) |
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 103-203 of human CD63 (NP_001771.1). |
| Sequence: | AGYVF RDKVM SEFNN NFRQQ MENYP KNNHT ASILD RMQAD FKCCG AANYT DWEKI PSMSK NRVPD SCCIN VTVGC GINFN EKAIH KEGCV EKIGG WLRKN V |
| Synonyms: | MLA1, ME491, LAMP-3, OMA81H, TSPAN30 |
| Calculated MW: | 26kDa |
| Observed MW: | 30-65kDa |
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