CD62L Monoclonal Antibody
- SKU:
- CAB24253
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- FC
Description
| Product Name: | CD62L Monoclonal Antibody |
| Product Code: | CAB24253 |
| Reactivity: | Human |
| Applications: | Flow Cytometry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC60035 |
| Reactivity: | Human |
| Tested Applications: | FC, ELISA |
| Key Applications: | Flow Cytometry |
| Recommended Dilution: | FC 1:500-1:000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3 |
| Cellular Location: | Membrane, Single-pass type I membrane protein |
This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 39-332 of human CD62L (NP_000646.3). |
| Sequence: | WTYHY SEKPM NWQRA RRFCR DNYTD LVAIQ NKAEI EYLEK TLPFS RSYYW IGIRK IGGIW TWVGT NKSLT EEAEN WGDGE PNNKK NKEDC VEIYI KRNKD AGKWN DDACH KLKAA LCYTA SCQPW SCSGH GECVE IINNY TCNCD VGYYG PQCQF VIQCE PLEAP ELGTM DCTHP LGNFS FSSQC AFSCS EGTNL TGIEE TTCGP FGNWS SPEPT CQVIQ CEPLS APDLG IMNCS HPLAS FSFTS ACTFI CSEGT ELIGK KKTIC ESSGI WSNPS PICQK LDKSF SMIKE GDYN |
| Synonyms: | SELL, CD62L, LAM1, LECAM1, LEU8, LNHR, LSEL, LYAM1, PLNHR, TQ1, L-selectin |
| Calculated MW: | 42kDa/43kDa |
| Observed MW: | Refer to figures |
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