CD62E/E-Selectin Monoclonal Antibody
- SKU:
- CAB23836
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- FC
Description
| Product Name: | CD62E/E-Selectin Monoclonal Antibody |
| Product Code: | CAB23836 |
| Reactivity: | Human |
| Applications: | Western blotting, Flow Cytometry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC61987 |
| Reactivity: | Human |
| Tested Applications: | WB, FC, ELISA |
| Key Applications: | Western blotting, Flow Cytometry |
| Recommended Dilution: | WB 1:500-1:1000, FC 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Recombinant Human E-Selectin/CD62E Protein(5ng) |
| Cellular Location: | Cell membrane, Single-pass type I membrane protein |
The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-230 of human CD62E/E-Selectin (NP_000441.2). |
| Sequence: | WSYNT STEAM TYDEA SAYCQ QRYTH LVAIQ NKEEI EYLNS ILSYS PSYYW IGIRK VNNVW VWVGT QKPLT EEAKN WAPGE PNNRQ KDEDC VEIYI KREKD VGMWN DERCS KKKLA LCYTA ACTNT SCSGH GECVE TINNY TCKCD PGFSG LKCEQ IVNCT ALESP EHGSL VCSHP LGNFS YNSSC SISCD RGYLP SSMET MQCMS SGEW |
| Synonyms: | SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2, E-selectin |
| Calculated MW: | 66kDa |
| Observed MW: | 110-120kDa |
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