CD45 Monoclonal Antibody (CAB23549)
- SKU:
- CAB23549
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Applications:
- FC
Description
| Product Name: | CD45 Monoclonal Antibody |
| Product Code: | CAB23549 |
| Reactivity: | Mouse |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence, Flow Cytometry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC60962 |
| Reactivity: | Mouse |
| Tested Applications: | WB, IHC-P, IF/ICC, FC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence, Flow Cytometry |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200, IF 1:50-1:200, FC 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | RAW264.7, Mouse spleen, Mouse thymus |
| Cellular Location: | Cell membrane |
Enables several functions, including heparan sulfate proteoglycan binding activity; heparin binding activity; and protein tyrosine phosphatase activity. Involved in several processes, including lymphocyte differentiation; positive regulation of macromolecule metabolic process; and regulation of signal transduction. Acts upstream of or within several processes, including lymphocyte differentiation; positive regulation of lymphocyte activation; and regulation of protein phosphorylation. Located in external side of plasma membrane; focal adhesion; and membrane raft. Is expressed in several structures, including 3rd branchial arch; alimentary system; cardiovascular system; hemolymphoid system; and placenta. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in hepatitis C; multiple sclerosis; severe combined immunodeficiency; and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive. Orthologous to human PTPRC (protein tyrosine phosphatase receptor type C).
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-566 of mouse CD45 (NP_001104786.2) |
| Sequence: | QTPTP SDELS TTENA LLLPQ SDPLP ARTTE STPPS ISERG NGSSE TTYHP GVLST LLPHL SPQPD SQTPS AGGAD TQTFS SQADN PTLTP APGGG TDPPG VPGER TVPGT IPADT AFPVD TPSLA RNSSA ASPTH TSNVS TTDIS SGASL TTLTP STLGL ASTDP PSTTI ATTTK QTCAA MFGNI TVNYT YESSN QTFKA DLKDV QNAKC GNEDC ENVLN NLEEC SQIKN ISVSN DSCAP ATTID LYVPP GTDKF SLHDC TPKEK ANTSI CLEWK TKNLD FRKCN SDNIS YVLHC EPENN TKCIR RNTFI PERCQ LDNLR AQTNY TCVAE ILYRG VKLVK NVINV QTDLG IPETP KPSCG DPAAR KTLVS WPEPV SKPES ASKPH GYVLC YKNNS EKCKS LPNNV TSFEV ESLKP YKYYE VSLLA YVNGK IQRNG TAEKC NFHTK ADRPD KVNGM KTSRP TDNSI NVTCG PPYET NGPKT FYILV VRSGG SFVTK YNKTN CQFYV DNLYY STDYE FLVSF HNGVY EGDSV IRNES TNFNA K |
| Synonyms: | loc, B220, Cd45, L-CA, Ly-5, T200, CD45R, Lyt-4 |
| Calculated MW: | 145KDa |
| Observed MW: | 180-250kDa |
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