Description
Product Name: | CD44 Monoclonal Antibody |
Product Code: | CAB24023 |
Reactivity: | Human |
Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Protein A purified |
Isotype: | IgG |
Clone No: | ARC52410 |
Reactivity: | Human |
Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
Recommended Dilution: | WB 1:2000-1:6000, IHC-P 1:1000-1:5000, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | HeLa |
Cellular Location: | Cell membrane, Single-pass type I membrane protein |
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-178 of human CD44 (NP_000601.3). |
Sequence: | AQIDL NITCR FAGVF HVEKN GRYSI SRTEA ADLCK AFNST LPTMA QMEKA LSIGF ETCRY GFIEG HVVIP RIHPN SICAA NNTGV YILTS NTSQY DTYCF NASAP PEEDC TSVTD LPNAF DGPIT ITIVN RDGTR YVQKG EYRTN PEDIY PSNPT DDDV |
Synonyms: | IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, CDW44, CSPG8, H-CAM, HCELL, ECM-III, HUTCH-1, HUTCH-I, ECMR-III, Hermes-1 |
Calculated MW: | 80kDa |
Observed MW: | 80kDa |