CD44 Monoclonal Antibody (CAB21919)
- SKU:
- CAB21919
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- FC
Description
| Product Name: | CD44 Monoclonal Antibody |
| Product Code: | CAB21919 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunohistochemistry, Flow Cytometry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC0464 |
| Reactivity: | Human |
| Tested Applications: | WB, IHC-P, FC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Flow Cytometry |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:500-1:1000, FC 1:20-1:50 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | U-251 MG |
| Cellular Location: | Cell membrane, Single-pass type I membrane protein |
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CD44 (P16070). |
| Sequence: | NNTGV YILTS NTSQY DTYCF NASAP PEEDC TSVTD LPNAF DGPIT ITIVN RDGTR YVQKG EYRTN PEDIY PSNPT DDDVS SGSSS ERSST SGGYI FYTFS T |
| Synonyms: | IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, CDW44, CSPG8, H-CAM, HCELL, ECM-III, HUTCH-1, HUTCH-I, ECMR-III, Hermes-1 |
| Calculated MW: | 82kDa |
| Observed MW: | 80kDa |
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