Description
system_update_alt Datasheet
Product Name: | CD44 Anti Human |
Product Sku: | CPAB0339 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human CD44 mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CD44 amino acids 21-145 purified from Ecoli. |
Clone: | P5C10AT. |
Reactivity: | Human |
Applications: | Western Blot, ELISA |
Purification Method: | CD44 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Isotype: | IgG2b |
Background: | CD44 is a cell-surface glycoprotein that plays a role in cell-cell interactions, cell adhesion and migration. CD44 is a receptor for hyaluronic acid and also interacts with other ligands, such as osteopontin, collagens, and matrix metalloproteinases. CD44 participates in a wide variety of cellular functions such as lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. CD44 and CD49d are putative activity markers and CD44 a potential novel therapeutic target in multiple sclerosis. Increased CD44 antigen is associated with relapses in non-small cell lung cancers. |
Synonyms: | MDU2, MDU3, MIC4, CDW44, CSPG8, HCELL, HUTCH-I, Phagocytic glycoprotein I, PGP-1, Extracellular matrix receptor-III, ECMR-III, Hermes antigen, Hyaluronate receptor, Heparan sulfate proteoglycan, Epican, CDw44. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |