CD42a Polyclonal Antibody
- SKU:
- CAB22234
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | CD42a Polyclonal Antibody |
| Product Code: | CAB22234 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | HEL |
| Cellular Location: | plasma membrane |
This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 17-140 of human CD42a (NP_000165.1). |
| Sequence: | TKDCP SPCTC RALET MGLWV DCRGH GLTAL PALPA RTRHL LLANN SLQSV PPGAF DHLPQ LQTLD VTQNP WHCDC SLTYL RLWLE DRTPE ALLQV RCASP SLAAH GPLGR LTGYQ LGSCG WQLQ |
| Synonyms: | GPIX, CD42a |
| Calculated MW: | 19kDa |
| Observed MW: | 19kDa |
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