CD4 Monoclonal Antibody
- SKU:
- CAB24719
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IP
- Applications:
- FC
Description
| Product Name: | CD4 Monoclonal Antibody |
| Product Code: | CAB24719 |
| Reactivity: | Mouse |
| Applications: | Western blotting, Immunoprecipitation, Flow Cytometry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC64069 |
| Reactivity: | Mouse |
| Tested Applications: | WB, IP, FC, ELISA |
| Key Applications: | Western blotting, Immunoprecipitation, Flow Cytometry |
| Recommended Dilution: | WB 1:500-1:1000, IP 1:50-1:200, FC 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.03% proclin300, 0.2% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | mouse thymus |
| Cellular Location: | Cell membrane |
Predicted to enable several functions, including interleukin-16 binding activity; interleukin-16 receptor activity; and protein homodimerization activity. Involved in helper T cell enhancement of adaptive immune response. Acts upstream of or within several processes, including defense response to Gram-negative bacterium; positive regulation of calcium-mediated signaling; and positive regulation of peptidyl-tyrosine phosphorylation. Located in endoplasmic reticulum; external side of plasma membrane; and membrane raft. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and liver and biliary system. Used to study type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in immunodeficiency 79. Orthologous to human CD4 (CD4 molecule).
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-394 of mouse CD4 (NP_038516.1). |
| Sequence: | KTLVL GKEGE SAELP CESSQ KKITV FTWKF SDQRK ILGQH GKGVL IRGGS PSQFD RFDSK KGAWE KGSFP LIINK LKMED SQTYI CELEN RKEEV ELWVF KVTFS PGTSL LQGQS LTLTL DSNSK VSNPL TECKH KKGKV VSGSK VLSMS NLRVQ DSDFW NCTVT LDQKK NWFGM TLSVL GFQST AITAY KSEGE SAEFS FPLNF AEENG WGELM WKAEK DSFFQ PWISF SIKNK EVSVQ KSTKD LKLQL KETLP LTLKI PQVSL QFAGS GNLTL TLDKG TLHQE VNLVV MKVAQ LNNTL TCEVM GPTSP KMRLT LKQEN QEARV SEEQK VVQVV APETG LWQCL LSEGD KVKMD SRIQV LSRGV NQT |
| Synonyms: | L3T4, Ly-4 |
| Calculated MW: | 51kDa |
| Observed MW: | 55kDa |
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