CD3E Monoclonal Antibody [PAT3H3AT] (CPAB0342)

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SKU:
CPAB0342
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT3H3AT
Applications:
WB
Applications:
ELISA

Description

system_update_alt Datasheet
Product Name:CD3E Antibody
Product Sku:CPAB0342
Size:5μg
Host Species:Mouse
Immunogen:Anti-human CD3E mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CD3E protein 23-126 amino acids purified from Ecoli.
Clone:PAT3H3AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:CD3E antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG1
Background:CD3-epsilonpolypeptide (CD3E) along with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, creates the T-cell receptor-CD3 complex. This complex has an imperative role in coupling antigen recognition to a number of intracellular signal-transduction pathways. The genes encoding the epsilon, gamma delta polypeptides are found in the same cluster on chromosome 11. The epsilon polypeptide plays a vital role in T-cell development. CD3E gene defects cause immunodeficiency. CD3E is also linked to a susceptibility to type I diabetes in women.
Synonyms:T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, T3E, TCRE.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.
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