CD3E Monoclonal Antibody [PAT3H3AT] (CPAB0342)
![CD3E Monoclonal Antibody [PAT3H3AT] (CPAB0342)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58564/63746/cd3e-monoclonal-antibody-pat3h3at-cpab0342__94902__27429.1706535143.jpg?c=1 "CD3E Monoclonal Antibody [PAT3H3AT] (CPAB0342)")
- SKU:
- CPAB0342
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- PAT3H3AT
- Applications:
- WB
- Applications:
- ELISA
![CD3E Monoclonal Antibody [PAT3H3AT] (CPAB0342)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58564/63746/cd3e-monoclonal-antibody-pat3h3at-cpab0342__94902__27429.1706535143.jpg?c=1&imbypass=on "CD3E Monoclonal Antibody [PAT3H3AT] (CPAB0342)")
Description
system_update_alt Datasheet
| Product Name: | CD3E Antibody |
| Product Sku: | CPAB0342 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human CD3E mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CD3E protein 23-126 amino acids purified from Ecoli. |
| Clone: | PAT3H3AT. |
| Reactivity: | Human |
| Applications: | Western Blot, ELISA |
| Purification Method: | CD3E antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
| Isotype: | IgG1 |
| Background: | CD3-epsilonpolypeptide (CD3E) along with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, creates the T-cell receptor-CD3 complex. This complex has an imperative role in coupling antigen recognition to a number of intracellular signal-transduction pathways. The genes encoding the epsilon, gamma delta polypeptides are found in the same cluster on chromosome 11. The epsilon polypeptide plays a vital role in T-cell development. CD3E gene defects cause immunodeficiency. CD3E is also linked to a susceptibility to type I diabetes in women. |
| Synonyms: | T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, T3E, TCRE. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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