CD3E Monoclonal Antibody (CAB23504)

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SKU:
CAB23504
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
Applications:
IHC
Applications:
FC

Description

Product Name:CD3E Monoclonal Antibody
Product Code:CAB23504
Reactivity:Human
Applications:Western blotting, Immunohistochemistry, Flow Cytometry
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC0327
Reactivity:Human
Tested Applications:WB, IHC-P, FC, ELISA
Key Applications:Western blotting, Immunohistochemistry, Flow Cytometry
Recommended Dilution:WB 1:500-1:1000, IHC-P 1:50-1:200, FC 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:Jurkat cells
Cellular Location:Cell membrane, Single-pass type I membrane protein

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

Immunogen:Recombinant protein of human CD3E.
Sequence:Email for sequence
Synonyms:T3E, TCRE, IMD18, CD3epsilon
Calculated MW:23kDa
Observed MW:Refer to figures
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