CD3E Monoclonal Antibody (CAB23504)
- SKU:
- CAB23504
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- FC
Description
| Product Name: | CD3E Monoclonal Antibody |
| Product Code: | CAB23504 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunohistochemistry, Flow Cytometry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC0327 |
| Reactivity: | Human |
| Tested Applications: | WB, IHC-P, FC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Flow Cytometry |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200, FC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Jurkat cells |
| Cellular Location: | Cell membrane, Single-pass type I membrane protein |
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
| Immunogen: | Recombinant protein of human CD3E. |
| Sequence: | Email for sequence |
| Synonyms: | T3E, TCRE, IMD18, CD3epsilon |
| Calculated MW: | 23kDa |
| Observed MW: | Refer to figures |
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