CD38 Monoclonal Antibody (CAB23037)

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SKU:
CAB23037
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
Applications:
FC

Description

Product Name:CD38 Monoclonal Antibody
Product Code:CAB23037
Reactivity:Mouse
Applications:Western blotting, Flow Cytometry
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC59835
Reactivity:Mouse
Tested Applications:WB, FC, ELISA
Key Applications:Western blotting, Flow Cytometry
Recommended Dilution:WB 1:500-1:1000, FC 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:Mouse spleen, Mouse colon
Cellular Location:Membrane, Single-pass type II membrane protein

This gene encodes a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Knockout mice deficient for this gene display altered humoral immune responses. In addition, knockout mice exhibit higher locomotor activity and defects in nurturing and social behaviors.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 45-304 of mouse CD38 (NP_031672.2).
Sequence:LRPRS LLVWT GEPTT KHFSD IFLGR CLIYT QILRP EMRDQ NCQEI LSTFK GAFVS KNPCN ITRED YAPLV KLVTQ TIPCN KTLFW SKSKH LAHQY TWIQG KMFTL EDTLL GYIAD DLRWC GDPST SDMNY VSCPH WSENC PNNPI TVFWK VISQK FAEDA CGVVQ VMLNG SLREP FYKNS TFGSV EVFSL DPNKV HKLQA WVMHD IEGAS SNACS SSSLN ELKMI VQKRN MIFAC VDNYR PARFL QCVKN PEHPS CRLNT
Synonyms:I-19, ADPRC 1, Cd38-rs1
Calculated MW:34kDa
Observed MW:52kDa
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