CD352/SLAMF6 Monoclonal Antibody (CAB23833)
- SKU:
- CAB23833
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- FC
Description
| Product Name: | CD352/SLAMF6 Monoclonal Antibody |
| Product Code: | CAB23833 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting, Immunohistochemistry, Flow Cytometry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC60903 |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, IHC-P, FC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Flow Cytometry |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200, FC 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Ramos, Daudi |
| Cellular Location: | Cell membrane, Single-pass type I membrane protein |
The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-215 of human CD352/SLAMF6 (NP_001171643.1) |
| Sequence: | SLTPL MVNGI LGESV TLPLE FPAGE KVNFI TWLFN ETSLA FIVPH ETKSP EIHVT NPKQG KRLNF TQSYS LQLSN LKMED TGSYR AQIST KTSAK LSSYT LRILR QLRNI QVTNH SQLFQ NMTCE LHLTC SVEDA DDNVS FRWEA LGNTL SSQPN LTVSW DPRIS SEQDY TCIAE NAVSN LSFSV SAQKL CE |
| Synonyms: | SLAMF6, CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000, SLAM family member 6 |
| Calculated MW: | 24kDa/37kDa |
| Observed MW: | 60kDa |
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