Description
Product Name: | CD33 Monoclonal Antibody |
Product Code: | CAB22704 |
Reactivity: | Human |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC57811 |
Reactivity: | Human |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:2000-1:8000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | U-937, THP-1 |
Cellular Location: | Cell membrane, Single-pass type I membrane protein |
Enables protein phosphatase binding activity and sialic acid binding activity. Involved in several processes, including negative regulation of cytokine production; negative regulation of monocyte activation; and positive regulation of protein tyrosine phosphatase activity. Located in several cellular components, including Golgi apparatus; external side of plasma membrane; and peroxisome.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-259 of human CD33 (NP_001763.3). |
Sequence: | DPNFW LQVQE SVTVQ EGLCV LVPCT FFHPI PYYDK NSPVH GYWFR EGAII SRDSP VATNK LDQEV QEETQ GRFRL LGDPS RNNCS LSIVD ARRRD NGSYF FRMER GSTKY SYKSP QLSVH VTDLT HRPKI LIPGT LEPGH SKNLT CSVSW ACEQG TPPIF SWLSA APTSL GPRTT HSSVL IITPR PQDHG TNLTC QVKFA GAGVT TERTI QLNVT YVPQN PTTGI FPGDG SGKQE TRAGV VH |
Synonyms: | p67, SIGLEC3, SIGLEC-3 |
Calculated MW: | 40kDa |
Observed MW: | 70-80kDa |