CD26/DPP4 Monoclonal Antibody
- SKU:
- CAB23297
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IP
- Applications:
- FC
Description
| Product Name: | CD26/DPP4 Monoclonal Antibody |
| Product Code: | CAB23297 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunoprecipitation, Flow Cytometry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC59223 |
| Reactivity: | Human |
| Tested Applications: | WB, IP, FC, ELISA |
| Key Applications: | Western blotting, Immunoprecipitation, Flow Cytometry |
| Recommended Dilution: | WB 1:1000-1:5000, IP 1:100-1:500, FC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HepG2, K-562(Negative control) |
| Cellular Location: | Apical cell membrane, Cell junction, Cell membrane, Cell projection, Membrane raft, Secreted, Single-pass type II membrane protein, invadopodium membrane, lamellipodium membrane |
The DPP4 gene encodes dipeptidyl peptidase 4, which is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic type II transmembrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. Dipeptidyl peptidase 4 is highly involved in glucose and insulin metabolism, as well as in immune regulation. This protein was shown to be a functional receptor for Middle East respiratory syndrome coronavirus (MERS-CoV), and protein modeling suggests that it may play a similar role with SARS-CoV-2, the virus responsible for COVID-19.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-766 of human CD26/DPP4(NP_001926.2) |
| Sequence: | NKGTD DATAD SRKTY TLTDY LKNTY RLKLY SLRWI SDHEY LYKQE NNILV FNAEY GNSSV FLENS TFDEF GHSIN DYSIS PDGQF ILLEY NYVKQ WRHSY TASYD IYDLN KRQLI TEERI PNNTQ WVTWS PVGHK LAYVW NNDIY VKIEP NLPSY RITWT GKEDI IYNGI TDWVY EEEVF SAYSA LWWSP NGTFL AYAQF NDTEV PLIEY SFYSD ESLQY PKTVR VPYPK AGAVN PTVKF FVVNT DSLSS VTNAT SIQIT APASM LIGDH YLCDV TWATQ ERISL QWLRR IQNYS VMDIC DYDES SGRWN CLVAR QHIEM STTGW VGRFR PSEPH FTLDG NSFYK IISNE EGYRH ICYFQ IDKKD CTFIT KGTWE VIGIE ALTSD YLYYI SNEYK GMPGG RNLYK IQLSD YTKVT CLSCE LNPER CQYYS VSFSK EAKYY QLRCS GPGLP LYTLH SSVND KGLRV LEDNS ALDKM LQNVQ MPSKK LDFII LNETK FWYQM ILPPH FDKSK KYPLL LDVYA GPCSQ KADTV FRLNW ATYLA STENI IVASF DGRGS GYQGD KIMHA INRRL GTFEV EDQIE AARQF SKMGF VDNKR IAIWG WSYGG YVTSM VLGSG SGVFK CGIAV APVSR WEYYD SVYTE RYMGL PTPED NLDHY RNSTV MSRAE NFKQV EYLLI HGTAD DNVHF QQSAQ ISKAL VDVGV DFQAM WYTDE DHGIA SSTAH QHIYT HMSHF IKQCF SLP |
| Synonyms: | CD26, ADABP, ADCP2, DPPIV, TP103 |
| Calculated MW: | 88kDa |
| Observed MW: | 120kDa |
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