CD239/BCAM Monoclonal Antibody (CAB23695)
- SKU:
- CAB23695
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- FC
Description
| Product Name: | CD239/BCAM Monoclonal Antibody |
| Product Code: | CAB23695 |
| Reactivity: | Human |
| Applications: | Western blotting, Flow Cytometry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC61168 |
| Reactivity: | Human |
| Tested Applications: | WB, FC, ELISA |
| Key Applications: | Western blotting, Flow Cytometry |
| Recommended Dilution: | WB 1:500-1:1000, FC 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | T-47D, SK-BR-3 |
| Cellular Location: | Membrane, Single-pass type I membrane protein |
This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 32-547 of human CD239/BCAM（NP_005572.2） |
| Sequence: | EVRLS VPPLV EVMRG KSVIL DCTPT GTHDH YMLEW FLTDR SGARP RLASA EMQGS ELQVT MHDTR GRSPP YQLDS QGRLV LAEAQ VGDER DYVCV VRAGA AGTAE ATARL NVFAK PEATE VSPNK GTLSV MEDSA QEIAT CNSRN GNPAP KITWY RNGQR LEVPV EMNPE GYMTS RTVRE ASGLL SLTST LYLRL RKDDR DASFH CAAHY SLPEG RHGRL DSPTF HLTLH YPTEH VQFWV GSPST PAGWV REGDT VQLLC RGDGS PSPEY TLFRL QDEQE EVLNV NLEGN LTLEG VTRGQ SGTYG CRVED YDAAD DVQLS KTLEL RVAYL DPLEL SEGKV LSLPL NSSAV VNCSV HGLPT PALRW TKDST PLGDG PMLSL SSITF DSNGT YVCEA SLPTV PVLSR TQNFT LLVQG SPELK TAEIE PKADG SWREG DEVTL ICSAR GHPDP KLSWS QLGGS PAEPI PGRQG WVSSS LTLKV TSALS RDGIS CEASN PHGNK RHVFH FGTVS PQTSQ A |
| Synonyms: | AU, LU, CD239, MSK19 |
| Calculated MW: | 67kDa |
| Observed MW: | 85kDa/78kDa |
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