Description
| Product Name: | CD22 Monoclonal Antibody |
| Product Code: | CAB23945 |
| Reactivity: | Mouse |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC62719 |
| Reactivity: | Mouse |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:100-1:2000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | A20 |
| Cellular Location: | Cell membrane, Single-pass type I membrane protein |
Enables CD4 receptor binding activity; protein phosphatase binding activity; and sialic acid binding activity. Involved in several processes, including negative regulation of calcium-mediated signaling; negative regulation of immunoglobulin production; and regulation of B cell proliferation. Located in external side of plasma membrane and neuronal cell body membrane. Is integral component of plasma membrane. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; liver and biliary system; and reproductive system. Orthologous to human CD22 (CD22 molecule).
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-151 of mouse CD22(NP_033975.3) |
| Sequence: | SSAND WTVDH PQTLF AWEGA CIRIP CKYKT PLPKA RLDNI LLFQN YEFDK ATKKF TGTVL YNATK TEKDP ESELY LSKQG RVTFL GNRID NCTLK IHPIR ANDSG NLGLR MTAGT ERWME PIHLN VSEKP F |
| Synonyms: | Lyb8, Lyb-8, A530093D23 |
| Calculated MW: | 89kDa/93kDa/97kDa |
| Observed MW: | 140kDa |