CD22 Monoclonal Antibody (CAB23160)
- SKU:
- CAB23160
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | CD22 Monoclonal Antibody |
| Product Code: | CAB23160 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC59246 |
| Reactivity: | Human |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Raji, Ramos |
| Cellular Location: | Cell membrane, Single-pass type I membrane protein |
Predicted to enable CD4 receptor binding activity; protein phosphatase binding activity; and sialic acid binding activity. Involved in B cell activation; negative regulation of B cell receptor signaling pathway; and regulation of endocytosis. Located in early endosome and recycling endosome.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-687 of human CD22 (NP_001762.2). |
| Sequence: | DSSKW VFEHP ETLY AWEGA C VWI PCTYR AL DG DLESF ILF H NPEYN KNTS KFDGT RLYES TKDG KVPSE Q KRV QFLGD KN KN CTLSI HPV H LNDSG QLGL RMESK TEKWM ERIH LNVSE R PFP PHIQL PP EI QESQE VTL T CLLNF SCYG YPIQL QWLLE GVPM RQAAV T STS LTIKS VF TR SELKF SPQ W SHHGK IVTC QLQDA DGKFL SNDT VQLNV K HTP KLEIK VT PS DAIVR EGD S VTMTC EVSS SNPEY TTVSW LKDG TSLKK Q NTF TLNLR EV TK DQSGK YCC Q VSNDV GPGR SEEVF LQVQY APEP STVQI L HSP AVEGS QV EF LCMSL ANP L PTNYT WYHN GKEMQ GRTEE KVHI PKILP W HAG TYSCV AE NI LGTGQ RGP G AELDV QYPP KKVTT VIQNP MPIR EGDTV T LSC NYNSS NP SV TRYEW KPH G AWEEP SLGV LKIQN VGWDN TTIA CAACN S WCS WASPV AL NV QYAPR DVR V RKIKP LSEI HSGNS VSLQC DFSS SHPKE V QFF WEKNG RL LG KESQL NFD S ISPED AGSY SCWVN NSIGQ TASK AWTLE V LYA PRRLR VS MS PGDQV MEG K SATLT CESD ANPPV SHYTW FDWN NQSLP Y HSQ KLRLE PV KV QHSGA YWC Q GTNSV GKGR SPLST LTVYY SPET IGRR |
| Synonyms: | SIGLEC2, SIGLEC-2 |
| Calculated MW: | 95kDa |
| Observed MW: | 130kDa/140kDa |
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