CD2 monoclonal antibody (PE) (AGIM0025)

Name: CD2 monoclonal antibody (PE) (AGIM0025)
SKU: AGIM0025
Availability: OutOfStock

(No reviews yet) Write a Review

Description

View AllClose

View AllClose

system_update_altDatasheetOverview

system_update_altDatasheetOverview

system_update_altDatasheetOverview

OverviewAntibody Name:Human CD2 Monoclonal Antibody (PE Conjugated)Antibody Code:AGEL1765Size:50 TestsClone:TS1/8Synon

OverviewProduct Name:CD2 Monoclonal AntibodyProduct Code:CAB23527Reactivity:MouseApplications:Western blottingH

system_update_altDatasheetOverview

system_update_altDatasheetOverview

OverviewProduct Name:CD2 Monoclonal AntibodyProduct Code:CAB23199Reactivity:HumanApplications:Western blotting, Immunohistochemis

OverviewProduct Name:CD2 Monoclonal AntibodyProduct Code:CAB23158Reactivity:HumanApplications:Western blotting, Immunoprecipitati

Isotype:	IgG1
Host Species:	Mouse
Storage:	Store at 4°C. Do not freeze. Avoid prolonged exposure to light.
Uniprot:	P06729
Background:	CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Morover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cellcell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.