CD1E Antibody (PACO00552)
- SKU:
- PACO00552
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CD1E Antibody |
| Antibody SKU: | PACO00552 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | WB:1:500-1:2000 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the Internal region of human CD1e. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | CD1E; T-cell surface glycoprotein CD1e; membrane-associated; hCD1e; R2G1; CD antigen CD1e |
| UniProt Protein Function: | T-cell surface glycoprotein CD1e, soluble binds diacetylated lipids, including phosphatidyl inositides and diacylated sulfoglycolipids, and is required for the presentation of glycolipid antigens on the cell surface. The membrane-associated form is not active. |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members. Many alternatively spliced transcript variants encoding different isoforms have been described. Additional transcript variants have been found; however, their biological validity has not been determined. [provided by RefSeq, Jun 2010] |
| UniProt Code: | P15812 |
| NCBI GenInfo Identifier: | 14030479 |
| NCBI Gene ID: | 913 |
| NCBI Accession: | AAK52914.1 |
| UniProt Secondary Accession: | P15812,Q5TDJ9, Q5TDK3, Q5TDK4, Q5TDK5, Q5TDK6, Q5TDK8 Q5TDL1, Q712E4, Q712E5 |
| UniProt Related Accession: | P15812 |
| Molecular Weight: | 32,303 Da |
| NCBI Full Name: | CD1E, partial |
| NCBI Synonym Full Names: | CD1e molecule |
| NCBI Official Symbol: | CD1E |
| NCBI Official Synonym Symbols: | R2; CD1A |
| NCBI Protein Information: | T-cell surface glycoprotein CD1e, membrane-associated |
| UniProt Protein Name: | T-cell surface glycoprotein CD1e, membrane-associated |
| UniProt Synonym Protein Names: | R2G1; CD_antigen: CD1e |
| Protein Family: | T-cell surface glycoprotein |
| UniProt Gene Name: | CD1E |
| UniProt Entry Name: |
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