CD155/PVR Monoclonal Antibody
- SKU:
- CAB23084
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | CD155/PVR Monoclonal Antibody |
| Product Code: | CAB23084 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC59175 |
| Reactivity: | Human |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | A549 |
| Cellular Location: | Cell membrane, Secreted |
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-343 of human CD155/PVR (NP_006496.4). |
| Sequence: | WPPPG TGDVV VQAPT QVPGF LGDSV TLPCY LQVPN MEVTH VSQLT WARHG ESGSM AVFHQ TQGPS YSESK RLEFV AARLG AELRN ASLRM FGLRV EDEGN YTCLF VTFPQ GSRSV DIWLR VLAKP QNTAE VQKVQ LTGEP VPMAR CVSTG GRPPA QITWH SDLGG MPNTS QVPGF LSGTV TVTSL WILVP SSQVD GKNVT CKVEH ESFEK PQLLT VNLTV YYPPE VSISG YDNNW YLGQN EATLT CDARS NPEPT GYNWS TTMGP LPPFA VAQGA QLLIR PVDKP INTTL ICNVT NALGA RQAEL TVQVK EGPPS EHSGI SRN |
| Synonyms: | PVS, HVED, CD155, NECL5, TAGE4, Necl-5 |
| Calculated MW: | 45kDa |
| Observed MW: | 70-80kDa |
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