CD146 Monoclonal Antibody
- SKU:
- CAB24343
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- FC
Description
| Product Name: | CD146 Monoclonal Antibody |
| Product Code: | CAB24343 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Flow Cytometry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC62356 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, FC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Flow Cytometry |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200, FC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | bEnd.3, mouse skin, rat lung, rat uterus |
| Cellular Location: | Membrane |
Predicted to be involved in angiogenesis and positive regulation of cell migration. Predicted to act upstream of or within heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Predicted to be located in external side of plasma membrane; extracellular space; and nucleus. Predicted to be active in plasma membrane. Is expressed in several structures, including adipose tissue; genitourinary system; gut; nervous system; and respiratory system. Orthologous to human MCAM (melanoma cell adhesion molecule).
| Immunogen: | Recombinant Protein corresponding to a sequence within amino acids 24-563 of mouse CD146 (NP_075548.2). |
| Sequence: | VPGEE KQPVP TPDLV EAEVG STALL KCGPS RASGN FSQVD WFLIH KERQI LIFRV HQGKG QREPG EYEHR LSLQD SVATL ALSHV TPHDE RMFLC KSKRP RLQDH YVELQ VFKAP EEPTI QANVV GIHVD RQELR EVATC VGRNG YPIPQ VLWYK NSLPL QEEEN RVHIQ SSQIV ESSGL YTLKS VLSAR LVKED KDAQF YCELS YRLPS GNHMK ESKEV TVPVF YPAEK VWVEV EPVGL LKEGD HVTIR CLTDG NPQPH FTINK KDPST GEMEE ESTDE NGLLS LEPAE KHHSG LYQCQ SLDLE TTITL SSDPL ELLVN YVSDV QVNPT APEVQ EGESL TLTCE AESNQ DLEFE WLRDK TGQLL GKGPV LQLNN VRREA GGRYL CMASV PRVPG LNRTQ LVSVG IFGSP WMALK ERKVW VQENA VLNLS CEASG HPQPT ISWNV NGSAT EWNPD PQTVV STLNV LVTPE LLETG AECTA SNSLG SNTTT IVLKL VTLTT LIPDS SQTTG LSTLT VSPHT RANST STEKK LPQPE SKGVV |
| Synonyms: | CD146, CD149, Muc18, s-endo, 1-gicerin, s-gicerin |
| Calculated MW: | 71kDa |
| Observed MW: | 100kDa, 110kDa, 120kDa |
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