CD146/MCAM Polyclonal Antibody
- SKU:
- CAB21488
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | CD146/MCAM Polyclonal Antibody |
| Product Code: | CAB21488 |
| Reactivity: | Human, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Positive Samples: | A375, HUVEC, PC-12 |
| Cellular Location: | Membrane, Single-pass type I membrane protein |
Involved in glomerular filtration and vascular wound healing. Acts upstream of or within angiogenesis. Located in external side of plasma membrane. Biomarker of chronic obstructive pulmonary disease and uveal melanoma.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 447-646 of human CD146/MCAM (NP_006491.2). |
| Sequence: | VLNLS CEASG HPRPT ISWNV NGTAS EQDQD PQRVL STLNV LVTPE LLETG VECTA SNDLG KNTSI LFLEL VNLTT LTPDS NTTTG LSTST ASPHT RANST STERK LPEPE SRGVV IVAVI VCILV LAVLG AVLYF LYKKG KLPCR RSGKQ EITLP PSRKS ELVVE VKSDK LPEEM GLLQG SSGDK RAPGD QGEKY IDLRH |
| Synonyms: | CD146, MUC18, HEMCAM, METCAM, MelCAM |
| Calculated MW: | 72kDa |
| Observed MW: | 120kDa |
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