CD146/MCAM Monoclonal Antibody
- SKU:
- CAB22195
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | CD146/MCAM Monoclonal Antibody |
| Product Code: | CAB22195 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC53805 |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:2000-1:10000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa |
| Cellular Location: | Membrane, Single-pass type I membrane protein |
Involved in glomerular filtration and vascular wound healing. Acts upstream of or within angiogenesis. Located in external side of plasma membrane. Biomarker of chronic obstructive pulmonary disease and uveal melanoma.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-350 of human CD146/MCAM (NP_006491.2). |
| Sequence: | GEAEQ PAPEL VEVEV GSTAL LKCGL SQSQG NLSHV DWFSV HKEKR TLIFR VRQGQ GQSEP GEYEQ RLSLQ DRGAT LALTQ VTPQD ERIFL CQGKR PRSQE YRIQL RVYKA PEEPN IQVNP LGIPV NSKEP EEVAT CVGRN GYPIP QVIWY KNGRP LKEEK NRVHI QSSQT VESSG LYTLQ SILKA QLVKE DKDAQ FYCEL NYRLP SGNHM KESRE VTVPV FYPTE KVWLE VEPVG MLKEG DRVEI RCLAD GNPPP HFSIS KQNPS TREAE EETTN DNGVL VLEPA RKEHS GRYEC QGLDL DTMIS LLSEP QELLV NYVSD VRVSP |
| Synonyms: | CD146, MUC18, HEMCAM, METCAM, MelCAM |
| Calculated MW: | 72kDa |
| Observed MW: | 120kDa |
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