Description
| Product Name: | CD132/IL-2 R gamma Monoclonal Antibody |
| Product Code: | CAB22037 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC54566 |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Jurkat, Mouse spleen, Mouse thymus |
| Cellular Location: | Membrane, Cell surface |
The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CD132/IL-2 R gamma (NP_000197.1). |
| Sequence: | TSKEN PFLFA LEAVV ISVGS MGLII SLLCV YFWLE RTMPR IPTLK NLEDL VTEYH GNFSA WSGVS KGLAE SLQPD YSERL CLVSE IPPKG GALGE GPGAS P |
| Synonyms: | P64, CIDX, IMD4, CD132, SCIDX, IL-2RG, SCIDX1 |
| Calculated MW: | 42kDa |
| Observed MW: | 50-70kDa |