Description
Product Name: | CD132/IL-2 R gamma Monoclonal Antibody |
Product Code: | CAB22037 |
Reactivity: | Human, Mouse |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC54566 |
Reactivity: | Human, Mouse |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:1000-1:5000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | Jurkat, Mouse spleen, Mouse thymus |
Cellular Location: | Membrane, Cell surface |
The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CD132/IL-2 R gamma (NP_000197.1). |
Sequence: | TSKEN PFLFA LEAVV ISVGS MGLII SLLCV YFWLE RTMPR IPTLK NLEDL VTEYH GNFSA WSGVS KGLAE SLQPD YSERL CLVSE IPPKG GALGE GPGAS P |
Synonyms: | P64, CIDX, IMD4, CD132, SCIDX, IL-2RG, SCIDX1 |
Calculated MW: | 42kDa |
Observed MW: | 50-70kDa |