CD123 Polyclonal Antibody
- SKU:
- CAB22111
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | CD123 Polyclonal Antibody |
| Product Code: | CAB22111 |
| Reactivity: | Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse spleen |
| Cellular Location: | external side of plasma membrane, plasma membrane |
The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-305 of human CD123 (NP_002174.1). |
| Sequence: | KEDPN PPITN LRMKA KAQQL TWDLN RNVTD IECVK DADYS MPAVN NSYCQ FGAIS LCEVT NYTVR VANPP FSTWI LFPEN SGKPW AGAEN LTCWI HDVDF LSCSW AVGPG APADV QYDLY LNVAN RRQQY ECLHY KTDAQ GTRIG CRFDD ISRLS SGSQS SHILV RGRSA AFGIP CTDKF VVFSQ IEILT PPNMT AKCNK THSFM HWKMR SHFNR KFRYE LQIQK RMQPV ITEQV RDRTS FQLLN PGTYT VQIRA RERVY EFLSA WSTPQ RFECD QEEGA NTRAW R |
| Synonyms: | IL3R, CD123, IL3RX, IL3RY, IL3RAY, hIL-3Ra, IL-3R-alpha |
| Calculated MW: | 43kDa |
| Observed MW: | 70kDa |
Related Products
Talacotuzumab (Anti-CD123) Biosimilar Antibody
Biotin Anti-Human CD123 Antibody [6H6]
PerCP/Cyanine5.5 Anti-Human CD123 Antibody [6H6]
Anti-CD123 Biotinylated Recombinant Rabbit Monoclonal Antibody (HDLA006)
](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/590x590/products/12462/16514/human-cd123-monoclonal-antibody-af647-conjugated-6h6agel1460__15789__69149.1706270029.jpg?c=1 "Human CD123 Monoclonal Antibody (AF647 Conjugated) [6H6](AGEL1460)")
Human CD123 Monoclonal Antibody (AF647 Conjugated) [6H6](AGEL1460)
Anti-CD123 Biotinylated Recombinant Rabbit Monoclonal Antibody (HDLA005)
Anti-CD123 Biotinylated Recombinant Rabbit Monoclonal Antibody (HDLA007)
](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/590x590/products/12459/16511/human-cd123-monoclonal-antibody-pe-conjugated-6h6agel1456__15181__10889.1706270028.jpg?c=1 "Human CD123 Monoclonal Antibody (PE Conjugated) [6H6](AGEL1456)")
Human CD123 Monoclonal Antibody (PE Conjugated) [6H6](AGEL1456)
](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/590x590/products/12460/16512/human-cd123-monoclonal-antibody-pecyanine5-conjugated-6h6agel1458__90635__95484.1706270029.jpg?c=1 "Human CD123 Monoclonal Antibody (PE/Cyanine5 Conjugated) [6H6](AGEL1458)")