Description
Product Name: | CD102 (ICAM2) Monoclonal Antibody |
Product Code: | CAB23245 |
Reactivity: | Human, Mouse |
Applications: | Western blotting, Immunohistochemistry |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC59377 |
Reactivity: | Human, Mouse |
Tested Applications: | WB, IHC-P, ELISA |
Key Applications: | Western blotting, Immunohistochemistry |
Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | Jurkat, HUVEC |
Cellular Location: | Membrane, Single-pass type I membrane protein |
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-223 of human CD102 (ICAM2) (NP_000864.2). |
Sequence: | KVFEV HVRPK KLAV EPKGS L EVN CSTTC NQ PE VGGLE TSL D KILLD EQAQ WKHYL VSNIS HDTV LQCHF T CSG KQESM NS NV SVYQP PRQ V ILTLQ PTLV AVGKS FTIEC RVPT VEPLD S LTL FLFRG NE TL HYETF GKA A PAPQE ATAT FNSTA DREDG HRNF SCLAV L DLM SRGGN IF HK HSAPK MLE I YEPVS DSQ |
Synonyms: | CD102 |
Calculated MW: | 30KDa |
Observed MW: | 45kDa/55-80kDa |