Description
system_update_altDatasheet
Product Name: | CD10 monoclonal antibody (FITC ) |
Product Code: | AGIM0307 |
Size: | 100 µL |
Reactivity: | Human |
Clone: | LT10 |
Applications: | Flow Cytometry |
Conjugate: | FITC |
Isotype: | IgG1 |
Host Species: | Mouse |
Storage: | Store at 4°C. Do not freeze. Avoid prolonged exposure to light. |
Uniprot: | P08473 |
Background: | CD10 (neutral endopeptidase NEP, common acute lymphocytic leukemia antigen CALLA, membrane metallo-endopeptidase MME, enkefalinase) is a 100-kDa cell surface zinc metalloprotease cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptids. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems. |