CD10/MME Monoclonal Antibody (CAB23509)

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SKU:
CAB23509
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
Applications:
IHC
Applications:
IF

Description

Product Name:CD10/MME Monoclonal Antibody
Product Code:CAB23509
Reactivity:Human, Mouse, Rat
Applications:Western blotting, Immunohistochemistry, Immunofluorescence
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC55336
Reactivity:Human, Mouse, Rat
Tested Applications:WB, IHC-P, IF/ICC, ELISA
Key Applications:Western blotting, Immunohistochemistry, Immunofluorescence
Recommended Dilution:WB 1:1000-1:5000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:Daudi, Mouse lung, Rat kidney
Cellular Location:Cell membrane

The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 52-750 of human CD10/MME (NP_000893.2).
Sequence:YDDGI CKSSD CIKSA ARLIQ NMDAT TEPCT DFFKY ACGGW LKRNV IPETS SRYGN FDILR DELEV VLKDV LQEPK TEDIV AVQKA KALYR SCINE SAIDS RGGEP LLKLL PDIYG WPVAT ENWEQ KYGAS WTAEK AIAQL NSKYG KKVLI NLFVG TDDKN SVNHV IHIDQ PRLGL PSRDY YECTG IYKEA CTAYV DFMIS VARLI RQEER LPIDE NQLAL EMNKV MELEK EIANA TAKPE DRNDP MLLYN KMTLA QIQNN FSLEI NGKPF SWLNF TNEIM STVNI SITNE EDVVV YAPEY LTKLK PILTK YSARD LQNLM SWRFI MDLVS SLSRT YKESR NAFRK ALYGT TSETA TWRRC ANYVN GNMEN AVGRL YVEAA FAGES KHVVE DLIAQ IREVF IQTLD DLTWM DAETK KRAEE KALAI KERIG YPDDI VSNDN KLNNE YLELN YKEDE YFENI IQNLK FSQSK QLKKL REKVD KDEWI SGAAV VNAFY SSGRN QIVFP AGILQ PPFFS AQQSN SLNYG GIGMV IGHEI THGFD DNGRN FNKDG DLVDW WTQQS ASNFK EQSQC MVYQY GNFSW DLAGG QHLNG INTLG ENIAD NGGLG QAYRA YQNYI KKNGE EKLLP GLDLN HKQLF FLNFA QVWCG TYRPE YAVNS IKTDV HSPGN FRIIG TLQNS AEFSE AFHCR KNSYM NPEKK CRVW
Synonyms:NEP, SFE, CD10, CALLA, CMT2T, SCA43
Calculated MW:86kDa
Observed MW:100kDa
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