CCNL1 Antibody (PACO23690)
- SKU:
- PACO23690
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CCNL1 Antibody (PACO23690) |
| Antibody SKU: | PACO23690 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human Cyclin-L1. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Cyclin-L1 antibody. |
 | Western blot analysis of extracts from HeLa cells (Lane 2), A549 cells (Lane 3) and HepG2 cells (Lane 4), using Cyclin-L1 antiobdy. The lane on the left is treated with systhesized peptide. |
 | Western blot analysis of extracts from HepG2 cells, using Cyclin-L1 antibody. |
| Background: | Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Seems to be involved in the regulation of RNA polymerase II (pol II). Functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). Inhibited by the CDK-specific inhibitor p21. |
| Synonyms: | Cyclin-L; CCNL1; |
| UniProt Protein Function: | CCNL1: cyclin L1, a member of the cyclin family. Associates with the PITSLRE kinase and is involved in pre-mRNA processing. |
| UniProt Protein Details: | Protein type:Cell cycle regulation; Oncoprotein Chromosomal Location of Human Ortholog: 3q25.31 Cellular Component: nuclear speck; nucleus Molecular Function:protein kinase binding Biological Process: RNA processing; transcription, DNA-dependent; regulation of transcription, DNA-dependent; regulation of cyclin-dependent protein kinase activity |
| UniProt Code: | Q9UK58 |
| NCBI GenInfo Identifier: | 9945320 |
| NCBI Gene ID: | |
| NCBI Accession: | NP_064703.1 |
| Molecular Weight: | ~ 60kDa |
| NCBI Full Name: | cyclin-L1 isoform 1 |
| UniProt Protein Name: | Cyclin-L1 |
| Protein Family: | Packaging protein |
| UniProt Gene Name: | CCNL1 |
| UniProt Entry Name: | CCNL1_HUMAN |
| Antibodies | ELISA Kits |
| CCNL1 Antibody (PACO00657) | Cyclin L1 Colorimetric Cell-Based ELISA Kit |
| CCNL1 Antibody (PACO08255) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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