Description
| Antibody Name: | Ccl25 Antibody (PACO32668) |
| Antibody SKU: | PACO32668 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse C-C motif chemokine 25 protein (25-144AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. |
| Synonyms: | C-C motif chemokine 25 (Chemokine TECK) (Small-inducible cytokine A25) (Thymus-expressed chemokine), Ccl25, Scya25 Teck |
| UniProt Protein Function: | CCL25: Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Belongs to the intercrine beta (chemokine CC) family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Motility/polarity/chemotaxis; Chemokine; Secreted Cellular Component: extracellular space; extracellular region Molecular Function:protein binding; chemokine activity; chemokine receptor binding; CCR10 chemokine receptor binding; cytokine activity Biological Process: G-protein coupled receptor protein signaling pathway; immune response; inflammatory response; positive regulation of cell-matrix adhesion; chemotaxis; leukocyte migration |
| UniProt Code: | O35903 |
| NCBI GenInfo Identifier: | 3122923 |
| NCBI Gene ID: | 20300 |
| NCBI Accession: | O35903.1 |
| Molecular Weight: | 16,714 Da |
| NCBI Full Name: | C-C motif chemokine 25 |
| UniProt Protein Name: | C-C motif chemokine 25 |
| UniProt Synonym Protein Names: | Chemokine TECK; Small-inducible cytokine A25; Thymus-expressed chemokine |
| Protein Family: | C-C motif chemokine |
| UniProt Gene Name: | Ccl25 |
| UniProt Entry Name: | CCL25_MOUSE |