Description
Product Name: | CCHCR1 Polyclonal Antibody |
Product Code: | CAB8221 |
Reactivity: | Human |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:2000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Cellular Location: | Cytoplasm, Nucleus |
This gene encodes a protein with five coiled-coil alpha-helical rod domains that is thought to act as a regulator of mRNA metabolism through its interaction with mRNA-decapping protein 4. It localizes to P-bodies, the site of mRNA metabolism, with an N-terminus that is required for this subcellular localization, suggesting it is a P-body component. Naturally occurring mutations in this gene are associated with psoriasis.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 536-835 of human CCHCR1 (NP_001099033.1). |
Sequence: | ALAQL RQESC PLPPP VTDVS LELQQ LREER NRLDA ELQLS ARLIQ QEVGR AREQG EAERQ QLSKV AQQLE QELQQ TQESL ASLGL QLEVA RQGQQ ESTEE AASLR QELTQ QQELY GQALQ EKVAE VETRL REQLS DTERR LNEAR REHAK AVVSL RQIQR RAAQE KERSQ ELRRL QEEAR KEEGQ RLARR LQELE RDKNL MLATL QQEGL LSRYK QQRLL TVLPS LLDKK KSVVS SPRPP ECSAS APVAA AVPTR ESIKG SLSVL LDDLQ DLSEA ISKEE AVCQG DNLDR CSSSN PQMSS |
Synonyms: | HCR, SBP, pg8, C6orf18 |
Calculated MW: | 89kDa |
Observed MW: | Refer to figures |