CCDC103 Antibody (PACO37738)
- SKU:
- PACO37738
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CCDC103 Antibody (PACO37738) |
| Antibody SKU: | PACO37738 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Coiled-coil domain-containing protein 103 protein (1-242AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. All lanes: CCDC103 antibody at 5µg/ml + Mouse heart tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 28, 12 kDa. Observed band size: 111 kDa. |
| Background: | Dynein-attachment factor required for cilia motility. |
| Synonyms: | Coiled-coil domain-containing protein 103, CCDC103 |
| UniProt Protein Function: | CCDC103: Dynein-attachment factor required for cilia motility. Defects in CCDC103 are the cause of primary ciliary dyskinesia type 17 (CILD17). A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome. Belongs to the CCDC103/PR46b family.Chromosomal Location of Human Ortholog: 17q21.31Cellular Component: cytoplasm; axonemeMolecular Function: protein homodimerization activityBiological Process: cell projection organization and biogenesis; heart loopingDisease: Ciliary Dyskinesia, Primary, 17 |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a protein that contains a coiled-coil domain. [provided by RefSeq, Apr 2012] |
| UniProt Code: | Q8IW40 |
| NCBI GenInfo Identifier: | 385719210 |
| NCBI Gene ID: | 388389 |
| NCBI Accession: | NP_001245328.1 |
| UniProt Secondary Accession: | Q8IW40,A8K145, B8ZZU0 |
| UniProt Related Accession: | Q8IW40 |
| Molecular Weight: | 11,276 Da |
| NCBI Full Name: | coiled-coil domain-containing protein 103 isoform 4 |
| NCBI Synonym Full Names: | coiled-coil domain containing 103 |
| NCBI Official Symbol: | CCDC103 |
| NCBI Official Synonym Symbols: | SMH; PR46b; CILD17 |
| NCBI Protein Information: | coiled-coil domain-containing protein 103 |
| UniProt Protein Name: | Coiled-coil domain-containing protein 103 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Coiled-coil domain-containing protein |
| UniProt Gene Name: | CCDC103 |
| UniProt Entry Name: | CC103_HUMAN |
Related Products
SPEF2 Antibody
Overview Product Name:SPEF2 AntibodyProduct Code:PACO64977Size:50µLTarget Names:SPEF2Species Reactivity:HumanHos
ompF Antibody
Overview Product Name:ompF AntibodyProduct Code:PACO64865Size:50µLTarget Names:ompFSpecies Reactivity:Escherichia coli
Hmgb1 Antibody
Overview Product Name:Hmgb1 AntibodyProduct Code:PACO64769Size:50µLTarget Names:Hmgb1Species Reactivity:RatHost
RIMS4 Antibody
Overview Product Name:RIMS4 AntibodyProduct Code:PACO64925Size:50µLTarget Names:RIMS4Species Reactivity:HumanHos
C22orf39 Antibody
Overview Product Name:C22orf39 AntibodyProduct Code:PACO64621Size:50µLTarget Names:C22orf39Species Reactivity:Human<