CBR1 Monoclonal Antibody [4000000000000] (CPAB0442)

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SKU:
CPAB0442
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2a
Clone:
4000000000000
Applications:
WB
Applications:
ELISA

Description

system_update_alt Datasheet
Product Name:CBR1 Antibody
Product Sku:CPAB0442
Size:5μg
Host Species:Mouse
Immunogen:Anti-human CBR1 mAb is derived from hybridization of mouse SP2/ myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CBR1 protein.
Clone:4E12.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:Recombinant human CBR1 (1-277 aa ) purified from E coli.
Isotype:IgG2a
Background:CBR1 is a NADPH-dependent, monomeric, and cytosolic enzyme which is related to a family of short-chain dehydrogenases/reductases. CBR1 protein (277 a.a.) is broadly spread in human tissues such as liver, epidermis, stomach, small intestine, kidney, neuronal cells, and smooth muscle fiber. CBR1 metabolizes numerous toxic environmental quinones and pharmacological relevant substrates such as the anticancer drug, doxorubicin. The best substrates of CBR1 are quinones, including ubiquinone-1 and tocophrolquinone (vitamin E).
Synonyms:Carbonyl Reductase 1, SDR21C1, Prostaglandin-E(2) 9-reductase, NADPH-dependent carbonyl reductase 1, CBR, hCBR1, 15-hydroxyprostaglandin dehydrogenase, CRN.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.
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