CBLN1 Antibody (PACO00586)
- SKU:
- PACO00586
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CBLN1 Antibody |
| Antibody SKU: | PACO00586 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | WB:1:500-1:2000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | synthesized peptide derived from the C-terminal region of human Cerebellin 1. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | CBLN1; Cerebellin-1; Precerebellin |
| UniProt Protein Function: | CBLN1: Cerebellin-1 is required for synapse integrity and synaptic plasticity. Required for the ER export and secretion of CBLN3.Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 16q12.1Cellular Component: postsynaptic membrane; extracellular region; cell junctionMolecular Function: protein homodimerization activityBiological Process: heterophilic cell adhesion; positive regulation of synaptogenesis; synaptic transmission; nervous system development; protein secretion; cerebellar granule cell differentiation |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a cerebellum-specific precursor protein, precerebellin, with similarity to the globular (non-collagen-like) domain of complement component C1qB. Precerebellin is processed to give rise to several derivatives, including the hexadecapeptide, cerebellin, which is highly enriched in postsynaptic structures of Purkinje cells. Cerebellin has also been found in human and rat adrenals, where it has been shown to enhance the secretory activity of this gland. [provided by RefSeq, Aug 2008] |
| UniProt Code: | P23435 |
| NCBI GenInfo Identifier: | 116114 |
| NCBI Gene ID: | 869 |
| NCBI Accession: | P23435.1 |
| UniProt Secondary Accession: | P23435,P02682, Q52M09, B2RAN9 |
| UniProt Related Accession: | P23435 |
| Molecular Weight: | 21,097 Da |
| NCBI Full Name: | Cerebellin-1 |
| NCBI Synonym Full Names: | cerebellin 1 precursor |
| NCBI Official Symbol: | CBLN1 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | cerebellin-1; precerebellin |
| UniProt Protein Name: | Cerebellin-1 |
| UniProt Synonym Protein Names: | PrecerebellinCleaved into the following 2 chains:Cerebellin; CER; [des-Ser1]-cerebellin |
| Protein Family: | Cerebellin |
| UniProt Gene Name: | CBLN1 |
| UniProt Entry Name: | CBLN1_HUMAN |
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