Description
| Product Name: | CAVIN2 Polyclonal Antibody |
| Product Code: | CAB23889 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | A-549, Mouse heart, Rat lung |
This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 325-425 of human CAVIN2(NP_004648.1). |
| Sequence: | PNDQE EESFA EGHSE ASLAS ALVEG EIAEE AAEKA TSRGS NSGMD SNIDL TIVED EEEES VALEQ AQKVR YEGSY ALTSE EAERS DGDPV QPAVL QVHQT S |
| Synonyms: | SDR, SDPR, PS-p68, cavin-2 |
| Calculated MW: | 47KDa |
| Observed MW: | 47kDa |