CATSPER3 Antibody (PACO15941)
- SKU:
- PACO15941
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CATSPER3 Antibody (PACO15941) |
| Antibody SKU: | PACO15941 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human CATSPER3 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse testis tissue, Primary antibody: PACO15941(CATSPER3 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes. |
| Background: | CatSpers (cation channel, sperm associated proteins) are ion transport proteins located on the surface of sperm cells in the principal piece of the sperm tail. CatSpers are vital to sperm motility, fertilization and cAMP-mediated calcium influx in sperm. There are four CatSper proteins in mammalian sperm, namely CatSper (or CatSper1), CatSper2, CatSper3 and CatSper4. CatSper proteins contain a single, six-transmembrane-spanning segment and exhibit the voltage-dependent Ca2+ channel four-repeat structure. CatSper proteins are believed to assemble into a heterotetrameric complex, forming an alkalinization-activated Ca2+-selective channel. Mutations in any of the genes encoding CatSper family proteins can result in male infertility. CatSper3 plays an important role in the hyperactivated motility of sperm cells, a process that is required in the preparation of sperm for fertilization. |
| Synonyms: | cation channel, sperm associated 3 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q86XQ3 |
| NCBI GenInfo Identifier: | 29789451 |
| NCBI Gene ID: | 347732 |
| NCBI Accession: | NP_821138.1 |
| UniProt Secondary Accession: | Q86XQ3 |
| UniProt Related Accession: | Q86XQ3 |
| Molecular Weight: | |
| NCBI Full Name: | cation channel sperm-associated protein 3 |
| NCBI Synonym Full Names: | cation channel sperm associated 3 |
| NCBI Official Symbol: | CATSPER3 |
| NCBI Official Synonym Symbols: | CACRC |
| NCBI Protein Information: | cation channel sperm-associated protein 3 |
| UniProt Protein Name: | Cation channel sperm-associated protein 3 |
| UniProt Synonym Protein Names: | Ca(v)-like protein; One-repeat calcium channel-like protein |
| Protein Family: | |
| UniProt Gene Name: | CATSPER3 |
| UniProt Entry Name: | CTSR3_HUMAN |
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