Cathepsin G Monoclonal Antibody (CAB22048)
- SKU:
- CAB22048
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Cathepsin G Monoclonal Antibody |
| Product Code: | CAB22048 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC54792 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | THP-1, Mouse spleen, Rat spleen, Rat thymus |
| Cellular Location: | Cell surface |
The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, the encoded protein is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this gene.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 156-255 of human Cathepsin G (NP_001902.1). |
| Sequence: | TDTLR EVQLR VQRDR QCLRI FGSYD PRRQI CVGDR RERKA AFKGD SGGPL LCNNV AHGIV SYGKS SGVPP EVFTR VSSFL PWIRT TMRSF KLLDQ METPL |
| Synonyms: | CG, CATG |
| Calculated MW: | 29kDa |
| Observed MW: | 29kDa |
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