CASQ2 Monoclonal Antibody [PAT4E10AT] (CPAB0443)

Name: CASQ2 Monoclonal Antibody [PAT4E10AT] (CPAB0443)
SKU: CPAB0443
Availability: OutOfStock

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Product Name:	CASQ2 Antibody
Product Sku:	CPAB0443
Size:	5μg
Host Species:	Mouse
Immunogen:	Anti-human CASQ2 mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CASQ2 amino acids 2-399 purified from Ecoli.
Clone:	PAT4E10AT.
Reactivity:	Other bodies
Applications:	Western Blot, ELISA

Purification Method:	CASQ2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:	IgG1
Background:	CASQ2 belongs to the calsequestrin family and is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. CASQ2 is a calcium binding protein that stores calcium for muscle function. The discharge of calcium bound to CASQ2 through a calcium release channel activates muscle contraction. CASQ2 binds 40 to 50 moles of calcium. CASQ2 mutations result in stress-induced polymorphic ventricular tachycardia, also called catecholaminergic polymorphic ventricular tachycardia 2 which is known fir its bidirectional ventricular tachycardia that causes cardiac arrest.
Synonyms:	PDIB2, CASQ2, Calsequestrin-2, Calsequestrin cardiac muscle isoform, FLJ26321, FLJ93514.
Storage Buffer:	For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.