Description
Antibody Name: | CARF Antibody (PACO23380) |
Antibody SKU: | PACO23380 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from internal of human ALS2CR8. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot analysis of extracts from HuvEc cells, using ALS2CR8 antibody. |
![]() | Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using ALS2CR8 antibody. |
Background: | Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence. |
Synonyms: | Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein; Calcium-response factor; CaRF; Testis development protein NYD-SP24; |
UniProt Protein Function: | CARF: May be a transcription factor. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Transcription factorChromosomal Location of Human Ortholog: 2q33.2Cellular Component: nucleusMolecular Function: DNA binding; transcription factor activity |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q8N187 |
NCBI GenInfo Identifier: | 85540610 |
NCBI Gene ID: | 79800 |
NCBI Accession: | Q8N187.2 |
UniProt Secondary Accession: | Q8N187,Q8ND29, Q8WXC0, Q96J78, Q96Q38, Q96Q39, Q9H712 B4E1W7, G3V1K7 |
UniProt Related Accession: | Q8N187 |
Molecular Weight: | 72,385 Da |
NCBI Full Name: | Calcium-responsive transcription factor |
NCBI Synonym Full Names: | calcium responsive transcription factor |
NCBI Official Symbol: | CARF |
NCBI Official Synonym Symbols: | ALS2CR8; NYD-SP24 |
NCBI Protein Information: | calcium-responsive transcription factor |
UniProt Protein Name: | Calcium-responsive transcription factor |
UniProt Synonym Protein Names: | Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein; Calcium-response factor; CaRF; Testis development protein NYD-SP24 |
Protein Family: | Calcium-responsive transcription factor |
UniProt Gene Name: | CARF |
UniProt Entry Name: | CARTF_HUMAN |
Antibodies |
CARF Antibody (PACO00389) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |