Description
Antibody Name: | CARD6 Antibody (PACO23636) |
Antibody SKU: | PACO23636 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from human CARD6. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from HeLa cells, using CARD6 antibody. | |
Immunofluorescence analysis of HeLa cells, using CARD6 antibody. | |
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using CARD6 antibody. |
Background: | This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB. |
Synonyms: | Caspase recruitment domain-containing protein 6; CARD6; |
UniProt Protein Function: | May be involved in apoptosis. |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q52LR2 |
NCBI GenInfo Identifier: | 16554564 |
NCBI Gene ID: | 84674 |
NCBI Accession: | NP_115976.2 |
UniProt Secondary Accession: | Q52LR2,Q52LR2 |
UniProt Related Accession: | Q52LR2,Q9BX69 |
Molecular Weight: | Calculated: 116kDaObserved: 116kDa |
NCBI Full Name: | caspase recruitment domain-containing protein 6 |
NCBI Synonym Full Names: | caspase recruitment domain family member 6 |
NCBI Official Symbol: | CARD6 |
NCBI Official Synonym Symbols: | CINCIN1 |
NCBI Protein Information: | caspase recruitment domain-containing protein 6 |
UniProt Protein Name: | Caspase recruitment domain-containing protein 6 |
UniProt Synonym Protein Names: | |
Protein Family: | Caspase recruitment domain-containing protein |
UniProt Gene Name: | CARD6 |
UniProt Entry Name: |