Description
| Antibody Name: | CARD6 Antibody (PACO23636) | 
| Antibody SKU: | PACO23636 | 
| Size: | 100ul | 
| Host Species: | Rabbit | 
| Tested Applications: | ELISA, WB, IHC, IF | 
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 | 
| Species Reactivity: | Human | 
| Immunogen: | Synthesized peptide derived from human CARD6. | 
| Form: | Liquid | 
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | 
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | 
| Clonality: | Polyclonal | 
| Isotype: | IgG | 
| Conjugate: | Non-conjugated | 
![]()  | Western blot analysis of extracts from HeLa cells, using CARD6 antibody. | 
![]()  | Immunofluorescence analysis of HeLa cells, using CARD6 antibody. | 
![]()  | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using CARD6 antibody. | 
| Background: | This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB. | 
| Synonyms: | Caspase recruitment domain-containing protein 6; CARD6; | 
| UniProt Protein Function: | May be involved in apoptosis. | 
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB. [provided by RefSeq, Jul 2008] | 
| UniProt Code: | Q52LR2 | 
| NCBI GenInfo Identifier: | 16554564 | 
| NCBI Gene ID: | 84674 | 
| NCBI Accession: | NP_115976.2 | 
| UniProt Secondary Accession: | Q52LR2,Q52LR2 | 
| UniProt Related Accession: | Q52LR2,Q9BX69 | 
| Molecular Weight: | Calculated: 116kDaObserved: 116kDa | 
| NCBI Full Name: | caspase recruitment domain-containing protein 6 | 
| NCBI Synonym Full Names: | caspase recruitment domain family member 6 | 
| NCBI Official Symbol: | CARD6 | 
| NCBI Official Synonym Symbols: | CINCIN1 | 
| NCBI Protein Information: | caspase recruitment domain-containing protein 6 | 
| UniProt Protein Name: | Caspase recruitment domain-containing protein 6 | 
| UniProt Synonym Protein Names: | |
| Protein Family: | Caspase recruitment domain-containing protein | 
| UniProt Gene Name: | CARD6 | 
| UniProt Entry Name: | 
            

