CARD18 Antibody (PACO63271)
- SKU:
- PACO63271
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CARD18 Antibody (PACO63271) |
| Antibody SKU: | PACO63271 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Caspase recruitment domain-containing protein 18 protein (1-90AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO63271 diluted at 1:100 and staining in paraffin-embedded human heart tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Inhibits generation of IL-1-β by interacting with caspase-1 and preventing its association with RIP2. Down-regulates the release of IL1B. |
| Synonyms: | Caspase recruitment domain-containing protein 18 (Caspase-1 inhibitor Iceberg), CARD18, ICEBERG |
| UniProt Protein Function: | Inhibits generation of IL-1-beta by interacting with caspase-1 and preventing its association with RIP2. Down-regulates the release of IL1B. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P57730 |
| NCBI GenInfo Identifier: | 10954343 |
| NCBI Gene ID: | 59082 |
| NCBI Accession: | NP_067546.1 |
| UniProt Secondary Accession: | P57730,A2RRF8 |
| UniProt Related Accession: | P57730 |
| Molecular Weight: | 10,138 Da |
| NCBI Full Name: | caspase recruitment domain-containing protein 18 |
| NCBI Synonym Full Names: | caspase recruitment domain family member 18 |
| NCBI Official Symbol: | CARD18 |
| NCBI Official Synonym Symbols: | ICEBERG; UNQ5804; pseudo-ICE |
| NCBI Protein Information: | caspase recruitment domain-containing protein 18 |
| UniProt Protein Name: | Caspase recruitment domain-containing protein 18 |
| UniProt Synonym Protein Names: | Caspase-1 inhibitor Iceberg |
| Protein Family: | |
| UniProt Gene Name: | CARD18 |
| UniProt Entry Name: | CAR18_HUMAN |
Related Products
Human TP53 antibody(p53 antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
OSTN Antibody
Overview Product Name:OSTN AntibodyProduct Code:PACO64881Size:50µLTarget Names:OSTNSpecies Reactivity:HumanHost
CYP2A13 Antibody
Overview Product Name:CYP2A13 AntibodyProduct Code:PACO64657Size:50µLTarget Names:CYP2A13Species Reactivity:Human, Mouse
OR13C8 Antibody
Overview Product Name:OR13C8 AntibodyProduct Code:PACO64869Size:50µLTarget Names:OR13C8Species Reactivity:HumanH