CARD17 Antibody (PACO19390)
- SKU:
- PACO19390
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CARD17 Antibody (PACO19390) |
| Antibody SKU: | PACO19390 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human CARD17 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19390(CARD17 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19390(CARD17 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation. |
| Synonyms: | caspase recruitment domain family, member 17 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q5XLA6 |
| NCBI GenInfo Identifier: | 55925612 |
| NCBI Gene ID: | 440068 |
| NCBI Accession: | NP_001007233.1 |
| UniProt Secondary Accession: | Q5XLA6 |
| UniProt Related Accession: | Q5XLA6 |
| Molecular Weight: | 11,868 Da |
| NCBI Full Name: | caspase recruitment domain-containing protein 17 |
| NCBI Synonym Full Names: | caspase recruitment domain family, member 17 |
| NCBI Official Symbol: | CARD17 |
| NCBI Official Synonym Symbols: | INCA |
| NCBI Protein Information: | caspase recruitment domain-containing protein 17; Inhibitory CARD; caspase-1 inhibitor INCA; inhibitory caspase recruitment domain (CARD) protein; inhibitory caspase recruitment domain protein |
| UniProt Protein Name: | Caspase recruitment domain-containing protein 17 |
| UniProt Synonym Protein Names: | Caspase-1 inhibitor INCA; Inhibitory caspase recruitment domain protein |
| Protein Family: | Inclusion membrane protein |
| UniProt Gene Name: | CARD17 |
| UniProt Entry Name: | CAR17_HUMAN |
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