Description
| Antibody Name: | CAPN14 Antibody (PACO51386) |
| Antibody SKU: | PACO51386 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Calpain-14 protein (68-366AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human ovarian cancer using PACO51386 at dilution of 1:100. |
![]() | Immunofluorescent analysis of Hela cells using PACO51386 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Calcium-regulated non-lysosomal thiol-protease. |
| Synonyms: | Calpain-14 (EC 3.4.22) (Calcium-activated neutral proteinase 14) (CANP 14), CAPN14 |
| UniProt Protein Function: | Calcium-regulated non-lysosomal thiol-protease. |
| UniProt Protein Details: | |
| NCBI Summary: | Calpains are a family of cytosolic calcium-activated cysteine proteases involved in a variety of cellular processes including apoptosis, cell division, modulation of integrin-cytoskeletal interactions, and synaptic plasticity (Dear et al., 2000 [PubMed 10964513]). CAPN14 belongs to the calpain large subunit family.[supplied by OMIM, Mar 2008] |
| UniProt Code: | A8MX76 |
| NCBI GenInfo Identifier: | 223468608 |
| NCBI Gene ID: | 440854 |
| NCBI Accession: | NP_001138594 |
| UniProt Secondary Accession: | A8MX76,B3KRU9 |
| UniProt Related Accession: | A8MX76 |
| Molecular Weight: | 79 kDa |
| NCBI Full Name: | calpain-14 isoform 1 |
| NCBI Synonym Full Names: | calpain 14 |
| NCBI Official Symbol: | CAPN14 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | calpain-14 |
| UniProt Protein Name: | Calpain-14 |
| UniProt Synonym Protein Names: | Calcium-activated neutral proteinase 14; CANP 14 |
| Protein Family: | Calpain |
| UniProt Gene Name: | CAPN14 |
| UniProt Entry Name: |

