CAPN11 Antibody (PACO00502)
- SKU:
- PACO00502
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CAPN11 Antibody |
| Antibody SKU: | PACO00502 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | WB:1:500-1:2000 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the Internal region of human Calpain 11. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | CAPN11; Calpain-11; Calcium-activated neutral proteinase 11; CANP 11 |
| UniProt Protein Function: | CAPN11: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Belongs to the peptidase C2 family.Protein type: EC 3.4.22.-; ProteaseChromosomal Location of Human Ortholog: 6p12Cellular Component: acrosomeMolecular Function: calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; peptidase activityBiological Process: proteolysis |
| UniProt Protein Details: | |
| NCBI Summary: | Calpains constitute a family of intracellular calcium-dependent cysteine proteases. There are eight members in this superfamily. They consist of a variable 80 kDa subunit and an invariant 30 kDa subunit. This calpain protein appears to have protease activity and calcium-binding ability. A similar mouse protein may play a functional role in spermatogenesis and in the regulation of calcium-dependent signal transduction events during meiosis. [provided by RefSeq, Dec 2008] |
| UniProt Code: | Q9UMQ6 |
| NCBI GenInfo Identifier: | 218511961 |
| NCBI Gene ID: | 11131 |
| NCBI Accession: | Q9UMQ6.2 |
| UniProt Secondary Accession: | Q9UMQ6,Q5T3G1, Q8N4R5, B2RA64 |
| UniProt Related Accession: | Q9UMQ6 |
| Molecular Weight: | 84,423 Da |
| NCBI Full Name: | Calpain-11 |
| NCBI Synonym Full Names: | calpain 11 |
| NCBI Official Symbol: | CAPN11 |
| NCBI Official Synonym Symbols: | calpain11 |
| NCBI Protein Information: | calpain-11 |
| UniProt Protein Name: | Calpain-11 |
| UniProt Synonym Protein Names: | Calcium-activated neutral proteinase 11; CANP 11 |
| Protein Family: | Calpain |
| UniProt Gene Name: | CAPN11 |
| UniProt Entry Name: | CAN11_HUMAN |
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