CANX Monoclonal Antibody [PAT18B9AT] (CPAB0680)
![CANX Monoclonal Antibody [PAT18B9AT] (CPAB0680)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58900/64082/canx-monoclonal-antibody-pat18b9at-cpab0680__53838__82747.1706535253.jpg?c=1 "CANX Monoclonal Antibody [PAT18B9AT] (CPAB0680)")
- SKU:
- CPAB0680
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- PAT18B9AT
- Applications:
- WB
- Applications:
- ELISA
![CANX Monoclonal Antibody [PAT18B9AT] (CPAB0680)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58900/64082/canx-monoclonal-antibody-pat18b9at-cpab0680__53838__82747.1706535253.jpg?c=1&imbypass=on "CANX Monoclonal Antibody [PAT18B9AT] (CPAB0680)")
Description
system_update_alt Datasheet
| Product Name: | CANX Antibody |
| Product Sku: | CPAB0680 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human CANX mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CANX protein 21-481 amino acids purified from Ecoli. |
| Clone: | PAT18B9AT. |
| Reactivity: | Other bodies |
| Applications: | Western Blot, ELISA |
| Purification Method: | CANX antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
| Isotype: | IgG1 |
| Background: | Calnexin (CANX) belongs to the calnexin family of molecular chaperones. Calnexin is a calcium-binding, ER-associated protein that interacts briefly with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. Calnexin may also have a key role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Calnexin grants long-term protection of wild-type Shaker protein from ER-associated degradation. Polypeptide substrate recognition by Calnexin requires specific conformations of the Calnexin protein. Calnexin dwindles with aging and might contribute to a cytoprotection in an array of human age-related diseases. |
| Synonyms: | Calnexin, Major histocompatibility complex class I antigen-binding protein p88, p90, IP90, CANX, CNX, FLJ26570. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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