CAMTA1 Antibody (PACO19384)
- SKU:
- PACO19384
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CAMTA1 Antibody (PACO19384) |
| Antibody SKU: | PACO19384 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:15-1:50 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human CAMTA1 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using PACO19384(CAMTA1 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO19384(CAMTA1 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | Calmodulin-binding transcription activator 1 is a protein that in humans is encoded by the CAMTA1 gene. Normally expressed in non-neoplastic adult central nervous system tissues: detected in whole brain, cerebellum, brain cortex, occipital lobe, frontal lobe, temporal lobe, putamen. Expression levels are low in oligodendroglial tumors, and are reduced by half in oligodendroglioma and astrocytoma cases with 1p loss of heterozygosity. Detected in neuroblastic-type cultured neuroblastoma cells. |
| Synonyms: | calmodulin binding transcription activator 1 |
| UniProt Protein Function: | Transcriptional activator. May act as a tumor suppressor. |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene contains a CG1 DNA-binding domain, a transcription factor immunoglobulin domain, ankyrin repeats, and calmodulin-binding IQ motifs. The encoded protein is thought to be a transcription factor and may be a tumor suppressor. However, a translocation event is sometimes observed between this gene and the WWTR1 gene, with the resulting WWTR1-CAMTA1 oncoprotein leading to epithelioid hemangioendothelioma, a malignant vascular cancer. [provided by RefSeq, Mar 2017] |
| UniProt Code: | Q9Y6Y1 |
| NCBI GenInfo Identifier: | 307133748 |
| NCBI Gene ID: | 23261 |
| NCBI Accession: | NP_001182492.1 |
| UniProt Secondary Accession: | Q9Y6Y1,Q5VUE1, Q6V701, Q8WYI3, Q96S92, A7MBM4, G3V3Z7 |
| UniProt Related Accession: | Q9Y6Y1 |
| Molecular Weight: | 184 |
| NCBI Full Name: | calmodulin-binding transcription activator 1 isoform b |
| NCBI Synonym Full Names: | calmodulin binding transcription activator 1 |
| NCBI Official Symbol: | CAMTA1 |
| NCBI Official Synonym Symbols: | CANPMR |
| NCBI Protein Information: | calmodulin-binding transcription activator 1 |
| UniProt Protein Name: | Calmodulin-binding transcription activator 1 |
| UniProt Synonym Protein Names: | |
| Protein Family: | |
| UniProt Gene Name: | CAMTA1 |
| UniProt Entry Name: |
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