Description
Antibody Name: | CAMK2G/CAMK2B Antibody (PACO21838) |
Antibody SKU: | PACO21838 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthesized peptide derived from C-terminal of human CaMK2 β / γ . |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Tombes R.M., Biochim. Biophys. Acta 1355:281-292(1997). |
Clonality: | Polyclonal |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from Jurkat cells and COLO205 cells, using CaMK2 beta / gamma antibody. |
Synonyms: | Calcium/calmodulin-dependent protein kinase type II γ chain; EC 2.7.11.17; CaM-kinase II γ chain; CaM kinase II subunit gamma; CaMK-II subunit gamma |
UniProt Protein Function: | CAMK2G: a protein kinase of the CAMK2 family. A prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses that may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity. The holoenzyme is composed of four different chains: alpha, beta, gamma, and delta. The different chains assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. May interact with BAALC, MPDZ, SYN1 and synGAP. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 2.7.11.17; Protein kinase, CAMK; CAMK group; CAMK2 family Chromosomal Location of Human Ortholog: 10q22 Cellular Component: nucleoplasm; sarcoplasmic reticulum membrane; membrane; plasma membrane; cytosol Molecular Function:calmodulin binding; protein binding; protein homodimerization activity; calcium-dependent protein serine/threonine phosphatase activity; calmodulin-dependent protein kinase activity; ATP binding Biological Process: nervous system development; synaptic transmission; dephosphorylation; regulation of skeletal muscle adaptation; insulin secretion; calcium ion transport; protein amino acid autophosphorylation; cytokine and chemokine mediated signaling pathway; regulation of calcium ion transport; cell differentiation; protein oligomerization; G1/S transition of mitotic cell cycle |
UniProt Code: | Q13555 |
NCBI GenInfo Identifier: | 62512173 |
NCBI Gene ID: | |
NCBI Accession: | Q13555.3 |
UniProt Secondary Accession: | Q13555,Q13554, |
Molecular Weight: | ~ 50~80kDa |
NCBI Full Name: | Calcium/calmodulin-dependent protein kinase type II subunit gamma |
UniProt Protein Name: | Calcium/calmodulin-dependent protein kinase type II subunit gamma |
Protein Family: | Calcium/calmodulin-dependent protein kinase |
UniProt Gene Name: | CAMK2G |
UniProt Entry Name: | KCC2G_HUMAN |
Antibodies |
CAMK2G/CAMK2B Antibody (PACO00505) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |