Description
| Antibody Name: | CALR Antibody (PACO57688) |
| Antibody SKU: | PACO57688 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Pig |
| Immunogen: | Recombinant Pig Calreticulin protein (18-417AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis. |
| Synonyms: | Calreticulin (CRP55) (Calregulin) (Endoplasmic reticulum resident protein 60) (ERp60) (HACBP), CALR |
| UniProt Protein Function: | Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P28491 |
| NCBI GenInfo Identifier: | 291622246 |
| NCBI Gene ID: | 100381266 |
| NCBI Accession: | NP_001167604.1 |
| UniProt Secondary Accession: | P28491,D4N5N1 |
| UniProt Related Accession: | P28491 |
| Molecular Weight: | 48.64 kDa |
| NCBI Full Name: | calreticulin |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | CALR |
| NCBI Official Synonym Symbols: | CRP55; ERp60; HACBP; Calregulin |
| NCBI Protein Information: | calreticulin |
| UniProt Protein Name: | Calreticulin |
| UniProt Synonym Protein Names: | CRP55; Calregulin; Endoplasmic reticulum resident protein 60; ERp60; HACBP |
| Protein Family: | |
| UniProt Gene Name: | CALR |
| UniProt Entry Name: |